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Improvement of the Antiinflammatory and Antiallergic Activity of Bidens pilosa L. var. radiata SCHERFF Treated with Enzyme (Cellulosine)
https://stella.repo.nii.ac.jp/records/440
https://stella.repo.nii.ac.jp/records/4402b52fa9c-f0a3-44db-84b7-e256a45ed48b
| 名前 / ファイル | ライセンス | アクション |
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JHealthSci_54-3_p294.pdf (283.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2016-02-01 | |||||||||
| タイトル | ||||||||||
| タイトル | Improvement of the Antiinflammatory and Antiallergic Activity of Bidens pilosa L. var. radiata SCHERFF Treated with Enzyme (Cellulosine) | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | enzymatic digestion | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Bidens pilosa | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | antiinflammation | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | antiallergy | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | histamine | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Horiuchi, Masako
× Horiuchi, Masako
× Seyama, Yoshiyuki
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Bidens pilosa L. var. radiata SCHERFF (Tachiawayukisendangusa: Musashino Miyako Bidens Pilosa (MMBP)) has been reported to have antiinflammatory and antiallergic properties in the treatment of experimental diseases. We studied the antiinflammatory and anti-allergic effects of enzymatic digested MMBP (eMMBP), MMBP treated with Cellulosine, using an experimental inflammatory and allergic model. Oral administration of eMMBP suspension in carboxy-methyl-cellulose sodium solution inhibited the production of IgE 10 days after immunization with 2,4-dinitrophenylate (DNP)-ascaris in mice. Oral administration of eMMBP suspension inhibited dye exudation in rat skin induced by passive cutaneous anaphylaxis (PCA) and chemical mediators (histamine and substance P). The effects of eMMBP on the inhibition of histamine release from mast cells induced by compound 48/80 or antigen-antibody reaction was stronger than that of the hot-water extract (HWex). Caffeic acid and flavonoids (hyperin and isoquercitrin) in eMMBP are increased more than those in HWex of MMBP, as estimated using HPLC. These results suggest that eMMBP has antiinflammatory and antiallergic activity, and that enzymatic digestion enhances its antiallergic activity by the inhibition of histamine release from the mast cells due mainly to an increase in caffeic acid and flavonoids. The enzymatic digestion of MMBP might be useful in enhancing its antiinflammatory and antiallergic activities. | |||||||||
| 書誌情報 |
Journal of health science 巻 54, 号 3, p. 294-301, 発行日 2008-06-01 |
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| 出版者 | ||||||||||
| 出版者 | 日本薬学会 | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 13449702 | |||||||||
| 書誌レコードID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA11316464 | |||||||||
| 論文ID（NAID） | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | NAID | |||||||||
| 関連識別子 | 110006684377 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | info:10.1248/jhs.54.294 | |||||||||
| 権利 | ||||||||||
| 権利情報 | 日本薬学会 | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
